
Unfortunately the Binding of Isaac does not natively support any gamepad / controller / joystick.
You’ll want to go into your Steam settings and select to start Steam in Big Picture Mode. This gives a great interface for you to select and start games on your HTPC. Once steam and its Big Picture Mode are set up, all you need to do is hold down the big “X” button on your Xbox 360 controller, and steam will automatically start up. Steam and info about it’s Big Picture Mode can be found and installed from here.
I’d recommend purchasing The Binding of Isaac on Steam, or at least add your game key to your steam library (most Binding of Isaac keys should be able to be added).
Step #2: Install Steam and set up Big Picture Mode.
OR Simply get a wired Xbox 360 controller. #1: Wireless XBOX 360 Controller & #2: Wireless USB Gaming Receiver for Xbox 360 Controllers. The Xbox 360 controller is widely compatible with any games that support a controller, and integrates extremely well into windows and many other programs. The receiver is a little dongle that will plug into a USB slot on your computer and the wireless 360 controller can connect to that. I would recommend a wireless 360 controller with the wireless USB receiver. Windows 7 and higher will make installing the controller much easier. This article assumes you are running Windows on your HTPC. In that case be sure to turn down the detail and resolution settings in the game. Unfortunately it is a Flash based game, so much older machines may struggle somewhat. Luckily The Binding of Isaac does not require any sort of powerful computer, so pretty much anything should do. I’ll have to assume you already have your HTPC set up and working with your TV because there are too many variables to consider. Setup for the Binding of Isaac on an HTPC This article will let you know how to configure your living room computer, or HTPC (Home Theater PC) to play The Binding of Isaac. Playing games in the living room with a nice HDTV is the perfect setting, and just recently software and hardware have started making it convenient to play computer games in the living room. Lately I’ve also embarked on something of a return to “couch” gaming, at least some of the time. It offers tons of challenges, unlocks, secrets, and makes learning about the new items and overall game extremely fun.
It’s an addictive game, with elements of a shooter and adventure game mixed in an interesting, highly replayable way. I’ve been playing the Binding of Isaac for a while, having gotten into it watching some streamers like lethalfrag and cobaltstreak play it live.